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IL-1 beta 抗体

IL1B 适用: 小鼠, 大鼠 WB, IP, Neut, IF, IHC (p), EIA, RIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN616079
发货至: 中国
  • 抗原 See all IL-1 beta (IL1B) 抗体
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    适用
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    小鼠, 大鼠
    宿主
    • 175
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    克隆类型
    • 181
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    多克隆
    标记
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    This IL-1 beta antibody is un-conjugated
    应用范围
    • 184
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    Western Blotting (WB), Immunoprecipitation (IP), Neutralization (Neut), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody is primarily directed against mature, 17,000 MW Mouse IL1-beta and is useful in determining its presence in various assays. The antibody does not recognize Human IL1-beta or Mouse IL1-alpha. In ELISA formats and other immunoreactive assays, reactivity occurs with Rat IL1-beta. This antibody will recognize 10 % of the non-denatured (native) precursor 31,000 MW Mouse IL1-beta containing samples but will primarily detect all of the 17,000 MW mature molecule. However, in Immunoblot analysis, the usual procedure of heating the sample in SDS with or without reducing agents will facilitate denaturing of the 31,000 MW IL1-beta precursor molecule. Denatured 31,000 precursor IL1-beta will be recognized by this antibody.
    纯化方法
    DEAE Fractionation
    免疫原
    Recombinant Mouse IL-1 beta produced in E. coli Genename: IL1b Remarks: The MW of the recombinant Mouse IL-1 beta is 17 kDa
    Top Product
    Discover our top product IL1B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 0.1 mL of deionized water (or equivalent)
    浓度
    1.0 mg/mL (UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, None, None
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C or -20 °C. Following reconstitution store at -20 °C.
  • 抗原
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    别名
    Interleukin-1 beta / IL-1B (IL1B 产品)
    别名
    IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
    背景
    IL-1 beta (also known as Interleukin-1 beta, IL1-beta and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1beta is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
    基因ID
    16176
    NCBI登录号
    NP_032387
    UniProt
    P10749
    途径
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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