IL-1 beta 抗体
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北京 101111
Quick Overview for IL-1 beta 抗体 (ABIN616079)
抗原
See all IL-1 beta (IL1B) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is primarily directed against mature, 17,000 MW Mouse IL1-beta and is useful in determining its presence in various assays. The antibody does not recognize Human IL1-beta or Mouse IL1-alpha. In ELISA formats and other immunoreactive assays, reactivity occurs with Rat IL1-beta. This antibody will recognize 10 % of the non-denatured (native) precursor 31,000 MW Mouse IL1-beta containing samples but will primarily detect all of the 17,000 MW mature molecule. However, in Immunoblot analysis, the usual procedure of heating the sample in SDS with or without reducing agents will facilitate denaturing of the 31,000 MW IL1-beta precursor molecule. Denatured 31,000 precursor IL1-beta will be recognized by this antibody.
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纯化方法
- DEAE Fractionation
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免疫原
- Recombinant Mouse IL-1 beta produced in E. coli Genename: IL1b Remarks: The MW of the recombinant Mouse IL-1 beta is 17 kDa
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anti-Interleukin 1, beta (IL1B) (AA 101-200) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Pig, Cow WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) antibodyIL1B 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A6 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 161-269) antibodyIL1B 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 170-269) antibodyIL1B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 117-269) antibodyIL1B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 117-269) antibodyIL1B 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F12D5 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 1-269) antibodyIL1B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 148-174) antibodyIL1B 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21917 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 1-266) antibodyIL1B 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 1-269) antibodyIL1B 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with 0.1 mL of deionized water (or equivalent)
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浓度
- 1.0 mg/mL (UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, None, None
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C or -20 °C. Following reconstitution store at -20 °C.
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- Interleukin-1 beta / IL-1B
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背景
- IL-1 beta (also known as Interleukin-1 beta, IL1-beta and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1beta is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
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基因ID
- 16176
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NCBI登录号
- NP_032387
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UniProt
- P10749
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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