This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.,IL1R1,CD121A,D2S1473,IL-1R-alpha,IL1R,IL1RA,P80,Immunology & Inflammation,CD markers,Cytokines,Interleukins,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Hematopoietic Progenitors,Cardiovascular,IL1R1