IFT57 抗体 (AA 170-429)
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- 抗原 See all IFT57 抗体
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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抗原表位
- AA 170-429
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IFT57 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VEELEEESVA EDDAELTLNK VDEEFVEEET DNEENFIDLN VLKAQTYHLD MNETAKQEDI LESTTDAAEW SLEVERVLPQ LKVTIRTDNK DWRIHVDQMH QHRSGIESAL KETKGFLDKL HNEITRTLEK ISSREKYINN QLENLVQEYR AAQAQLSEAK ERYQQGNGGV TERTRLLSEV MEELEKVKQE MEEKGSSMTD GAPLVKIKQS LTKLKQETVE MDIRIGIVEH TLLQSKLKEK SNMTRNMHAT VIPEPATGFY
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 170-429 of human IFT57 (NP_060480.1).
- 亚型
- IgG
- Top Product
- Discover our top product IFT57 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
- 别名
- IFT57 (IFT57 产品)
- 别名
- Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
- 背景
- Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8 and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.,IFT57,ESRRBL1,HIPPI,MHS4R2,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,IFT57
- 分子量
- 49 kDa
- 基因ID
- 55081
- UniProt
- Q9NWB7
- 途径
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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