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IFT57 抗体 (AA 170-429)

IFT57 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142218
发货至: 中国
  • 抗原 See all IFT57 抗体
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 170-429
    适用
    • 29
    • 21
    • 17
    • 1
    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFT57 antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    VEELEEESVA EDDAELTLNK VDEEFVEEET DNEENFIDLN VLKAQTYHLD MNETAKQEDI LESTTDAAEW SLEVERVLPQ LKVTIRTDNK DWRIHVDQMH QHRSGIESAL KETKGFLDKL HNEITRTLEK ISSREKYINN QLENLVQEYR AAQAQLSEAK ERYQQGNGGV TERTRLLSEV MEELEKVKQE MEEKGSSMTD GAPLVKIKQS LTKLKQETVE MDIRIGIVEH TLLQSKLKEK SNMTRNMHAT VIPEPATGFY
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 170-429 of human IFT57 (NP_060480.1).
    亚型
    IgG
    Top Product
    Discover our top product IFT57 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    别名
    IFT57 (IFT57 产品)
    别名
    Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
    背景
    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8 and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.,IFT57,ESRRBL1,HIPPI,MHS4R2,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,IFT57
    分子量
    49 kDa
    基因ID
    55081
    UniProt
    Q9NWB7
    途径
    Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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