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IFT57 抗体 (Internal Region)

IFT57 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262481
发货至: 中国
  • 抗原 See all IFT57 抗体
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠, 犬
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFT57 antibody is un-conjugated
    应用范围
    • 27
    • 13
    • 13
    • 11
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    IFT57 Antibody detects endogenous levels of total IFT57.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IFT57, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IFT57 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    别名
    IFT57 (IFT57 产品)
    别名
    Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
    背景

    Description: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.

    Gene: IFT57

    分子量
    49 kDa
    基因ID
    55081
    UniProt
    Q9NWB7
    途径
    Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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