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- 抗原 See all CDKN2A 抗体
- CDKN2A (Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CDKN2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human CDKN2A/p16INK4a
- 亚型
- IgG
- Top Product
- Discover our top product CDKN2A Primary Antibody
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anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 8-156) antibody
CDKN2A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 104-131), (C-Term) antibodyCDKN2A 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19093 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) antibodyCDKN2A 适用: 人 WB, IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (pSer140) antibodyCDKN2A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21280 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) antibodyCDKN2A 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (pSer326) antibodyCDKN2A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 1-86) antibodyCDKN2A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 1-30), (N-Term) antibodyCDKN2A 适用: 人 WB 宿主: 兔 Polyclonal RB41435 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) antibodyCDKN2A 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (Center) antibodyCDKN2A 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CDKN2A (Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A))
- 别名
- CDKN2A (CDKN2A 产品)
- 别名
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Arf antibody, p16 antibody, MTS1 antibody, INK4A antibody, p19ARF antibody, p16Cdkn2a antibody, ARF antibody, CDK4I antibody, CDKN2 antibody, CMM2 antibody, INK4 antibody, MLM antibody, MTS-1 antibody, P14 antibody, P14ARF antibody, P16 antibody, P16-INK4A antibody, P16INK4 antibody, P16INK4A antibody, P19 antibody, P19ARF antibody, TP16 antibody, ARF-INK4a antibody, INK4a-ARF antibody, Ink4a/Arf antibody, Pctr1 antibody, p16(INK4a) antibody, p16INK4a antibody, p19
antibody, cyclin-dependent kinase inhibitor 2A antibody, cyclin dependent kinase inhibitor 2A antibody, Cdkn2a antibody, LOC100731972 antibody, LOC100340625 antibody, CDKN2A antibody - 背景
- This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene, this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. [provided by RefSeq, Sep 2012],ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Kinase,Signal Transduction,CDKN2A
- 分子量
- 17 kDa
- 基因ID
- 1029
- UniProt
- P42771
- 途径
- Mitotic G1-G1/S Phases, Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Autophagy, Positive Regulation of Response to DNA Damage Stimulus
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