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Src 抗体 (Tyr529)

Src 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5961535
发货至: 中国
  • 抗原 See all Src 抗体
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    抗原表位
    • 27
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    Tyr529
    适用
    • 215
    • 142
    • 119
    • 9
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    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
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    人, 小鼠, 大鼠
    宿主
    • 228
    • 19
    • 1
    克隆类型
    • 216
    • 32
    多克隆
    标记
    • 117
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    This Src antibody is un-conjugated
    应用范围
    • 188
    • 133
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    • 24
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    • 9
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ASV,Avian sarcoma virus,c SRC,CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA,cSrc,EC 2.7.10.2,Neuronal CSRC tyrosine specific protein kinase,Neuronal SRC,Oncogene SRC,OTTHUMP00000174476,OTTHUMP00000174477,p60 Src,p60-Src,p60Src,pp60c src,pp60c-src,pp60csrc,Proto oncogene tyrosine protein kinase Src,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,Protooncogene SRC,Protooncogene SRC Rous sarcoma,Src,SRC Oncogene,SRC proto oncogene non receptor tyrosine kinase,SRC,SRC1,Tyrosine kinase pp60c src,Tyrosine protein kinase SRC 1,Tyrosine protein kinase SRC1,v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog,V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian),v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from human c-Src around the non-phosphorylation site of Tyr529.
    亚型
    IgG
    Top Product
    Discover our top product Src Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    别名
    c-Src (Src 产品)
    别名
    AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
    物质类
    Viral Protein
    背景
    Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Once it is recruited to the activated integrins, by PTK2B, it phosphorylates CBL which in turn induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. Promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. Phosphorylates RUNX3 and COX2 on tyrosine residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances DDX58/RIG-I-elicited antiviral signaling.
    分子量
    60kDa
    基因ID
    6714
    UniProt
    P12931
    途径
    JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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