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PRKAA1/PRKAA2 抗体 (pThr172, pThr183)
适用: 人, 小鼠, 大鼠, 猴
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
PRKAA1/PRKAA2抗体详情
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抗原
See all PRKAA1/PRKAA2 products
PRKAA1/PRKAA2
(AMPK1/AMPK2)
抗原表位
All epitopes for PRKAA1/PRKAA2 抗体
pThr172, pThr183
适用
All reactivities for PRKAA1/PRKAA2 抗体
人, 小鼠, 大鼠, 猴
宿主
All hosts for PRKAA1/PRKAA2 抗体
兔
克隆类型
All clonalities for PRKAA1/PRKAA2 抗体
多克隆
标记
All conjugates for PRKAA1/PRKAA2 抗体
This PRKAA1/PRKAA2 antibody is un-conjugated
应用范围
All applications for PRKAA1/PRKAA2 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
特异性
PRKAA1,AMPK1,5'-AMP-activated protein kinase catalytic subunit alpha-1,AMPK subunit alpha-1,Acetyl-CoA carboxylase kinase,ACACA kinase,Hydroxymethylglutaryl-CoA reductase kinase,HMGCR kinase,Tau-protein kinase PRKAA1,PRKAA2,AMPK,
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human AMPKalpha1/2 around the phosphorylation site of Thr183/172
亚型
IgG
Alternatives
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
适用: 人, 小鼠, 大鼠, Pig, 绵羊
WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
PRKAA1/PRKAA2目标详情
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抗原
PRKAA1/PRKAA2
(AMPK1/AMPK2)
别名
AMPK alpha1/2 (PRKAA1/PRKAA2 产品 )
别名
AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, Ampk antibody, Ampka2 antibody, 2310008I11Rik antibody, A830082D05 antibody, AMPKalpha2 antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit antibody, PRKAA2 antibody, Prkaa2 antibody
背景
AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
分子量
62kDa
基因ID
5562, 5563
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