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SIGLEC7 抗体 (PE)

SIGLEC7 适用: 人 IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 5-386 PE
产品编号 ABIN576904
发货至: 中国
  • 抗原 See all SIGLEC7 抗体
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    适用
    • 83
    • 12
    • 3
    • 3
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    • 2
    • 1
    • 1
    宿主
    • 63
    • 20
    小鼠
    克隆类型
    • 63
    • 19
    • 1
    单克隆
    标记
    • 38
    • 12
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    • 6
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    • 1
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    This SIGLEC7 antibody is conjugated to PE
    应用范围
    • 62
    • 43
    • 39
    • 15
    • 10
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific for human CDw328, a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.
    纯化方法
    Affinity purified
    免疫原
    Monocyte-derived dendritic cells.

    Type of Immunogen: Cells
    克隆位点
    5-386
    亚型
    IgG1
    Top Product
    Discover our top product SIGLEC7 Primary Antibody
  • 应用备注
    Approved: Flo (1:1), IHC, IHC-Fr

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 1 mL distilled water.
    浓度
    Lot specific
    缓冲液
    Lyophilized powder from PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    avoid freezing
    储存条件
    4 °C
    储存方法
    4°C, avoid freezing.
  • 抗原
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    别名
    SIGLEC7 / CD328 (SIGLEC7 产品)
    别名
    SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
    背景
    Name/Gene ID: SIGLEC7
    Family: Immunoglobulin

    Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein
    基因ID
    27036
    UniProt
    Q9Y286
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