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SIGLEC7 抗体 (AA 377-467)

SIGLEC7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169566
发货至: 中国
  • 抗原 See all SIGLEC7 抗体
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    抗原表位
    • 10
    • 9
    • 8
    • 8
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    • 4
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    • 2
    • 1
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    AA 377-467
    适用
    • 83
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
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    宿主
    • 62
    • 21
    克隆类型
    • 62
    • 20
    • 1
    多克隆
    标记
    • 37
    • 12
    • 10
    • 7
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    • 5
    • 1
    • 1
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    This SIGLEC7 antibody is un-conjugated
    应用范围
    • 61
    • 42
    • 39
    • 16
    • 10
    • 6
    • 5
    • 3
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    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Sialic acid-binding Ig-like lectin 7 protein (377-467AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    别名
    SIGLEC7 (SIGLEC7 产品)
    别名
    SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
    背景

    Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

    Aliases: Adhesion inhibitory receptor molecule 1 antibody, Adhesion inhibitory receptor molecule 1, siglec 7 antibody, AIRM 1 antibody, AIRM-1 antibody, AIRM1 antibody, CD328 antibody, CD328 antigen antibody, CDw328 antibody, D siglec antibody, D-siglec antibody, HLDA 8 antibody, p75 antibody, p75/AIRM1 antibody, QA79 antibody, QA79 membrane protein antibody, Sialic acid binding Ig like lectin 7 antibody, Sialic acid binding immunoglobulin like lectin 7 antibody, Sialic acid-binding Ig-like lectin 7 antibody, SIGL7_HUMAN antibody, Siglec-7 antibody, SIGLEC19P antibody, SIGLEC7 antibody, SIGLECP2 antibody

    UniProt
    Q9Y286
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