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- 抗原 See all PARN 抗体
- PARN (Poly A Specific Ribonuclease (PARN))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARN antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity purified
- 免疫原
- A recombinant human protein corresponding to amino acids M1-Y301 was used as the immunogen for the PARN antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PARN Primary Antibody
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anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibody
PARN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibodyPARN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-301) antibodyPARN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 501-599) antibodyPARN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-280) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the PARN antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PARN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- PARN (Poly A Specific Ribonuclease (PARN))
- 别名
- PARN (PARN 产品)
- 别名
- parn-A antibody, xparn antibody, DAN antibody, RGD1565449 antibody, zgc:56067 antibody, 1200003I18Rik antibody, poly(A)-specific ribonuclease L homeolog antibody, poly(A)-specific ribonuclease antibody, poly(A)-specific ribonuclease (deadenylation nuclease) antibody, parn.L antibody, PARN antibody, Parn antibody, parn antibody
- 背景
- Poly(A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the PARN gene. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons.
- UniProt
- O95453
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