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PARN 抗体

PARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075117
发货至: 中国
  • 抗原 See all PARN 抗体
    PARN (Poly A Specific Ribonuclease (PARN))
    适用
    • 38
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 28
    • 10
    克隆类型
    • 31
    • 7
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARN antibody is un-conjugated
    应用范围
    • 27
    • 12
    • 11
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse PARN
    Top Product
    Discover our top product PARN Primary Antibody
  • 应用备注
    WB (H,M) 1:500-1:1000, IHC/IF (H) 1:900-1:1800
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PARN (Poly A Specific Ribonuclease (PARN))
    别名
    PARN (PARN 产品)
    别名
    parn-A antibody, xparn antibody, DAN antibody, RGD1565449 antibody, zgc:56067 antibody, 1200003I18Rik antibody, poly(A)-specific ribonuclease L homeolog antibody, poly(A)-specific ribonuclease antibody, poly(A)-specific ribonuclease (deadenylation nuclease) antibody, parn.L antibody, PARN antibody, Parn antibody, parn antibody
    背景
    The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    76 kDa
    基因ID
    74108
    UniProt
    Q8VDG3
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