PARN 抗体 (AA 1-301)
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- 抗原 See all PARN 抗体
- PARN (Poly A Specific Ribonuclease (PARN))
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抗原表位
- AA 1-301
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 品牌
- Picoband™
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for PARN detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human PARN recombinant protein (Position: M1-Y301).
- Top Product
- Discover our top product PARN Primary Antibody
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anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibody
PARN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibodyPARN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 501-599) antibodyPARN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-280) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (C-Term) antibodyPARN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PARN (Poly A Specific Ribonuclease (PARN))
- 别名
- PARN (PARN 产品)
- 别名
- parn-A antibody, xparn antibody, DAN antibody, RGD1565449 antibody, zgc:56067 antibody, 1200003I18Rik antibody, poly(A)-specific ribonuclease L homeolog antibody, poly(A)-specific ribonuclease antibody, poly(A)-specific ribonuclease (deadenylation nuclease) antibody, parn.L antibody, PARN antibody, Parn antibody, parn antibody
- 背景
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Synonyms: Poly(A)-specific ribonuclease PARN, Deadenylating nuclease, Deadenylation nuclease, Polyadenylate-specific ribonuclease, PARN, DAN
Tissue Specificity: Ubiquitous.
Background: Poly(A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the PARN gene. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons.
- UniProt
- O95453
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