CFTR / Cystic Fibrosis Transmembrane Regulator 抗体
-
- 抗原
- CFTR / Cystic Fibrosis Transmembrane Regulator
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- 非结合性
-
应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Purified
- 纯度
- Protein G affinity chromatography
- 免疫原
- A recombinant human partial protein was used as the immunogen for this recombinant CFTR antibody.
- 克隆位点
- RCFTR-1342
- 亚型
- IgG1 kappa
-
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody
适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
-
- 应用备注
-
Optimal dilution of the recombinant CFTR antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) - 限制
- 仅限研究用
-
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the recombinant CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
- 抗原
- CFTR / Cystic Fibrosis Transmembrane Regulator
- 背景
- CFTR functions as an ATP-gated anion channel, increasing the conductance for certain anions (e.g. Cl−,) to flow down their electrochemical gradient. ATP-driven conformational changes in CFTR open and close a gate to allow transmembrane flow of anions down their electrochemical gradient.[5] This in contrast to other ABC proteins, in which ATP-driven conformational changes fuel uphill substrate transport across cellular membranes. Essentially, CFTR is an ion channel that evolved as a 'broken' ABC transporter that leaks when in open conformation. CFTR is found in the epithelial cells of many organs including the lung, liver, pancreas, digestive tract, and the reproductive tract. [Wiki]
- 基因ID
- 1080
-
