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CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体

适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
产品编号 ABIN4949563
发货至: 中国
  • 抗原
    CFTR / Cystic Fibrosis Transmembrane Regulator
    抗原表位
    AA 258-385
    适用
    • 9
    • 4
    宿主
    • 5
    • 4
    小鼠
    克隆类型
    • 9
    单克隆
    标记
    • 9
    非结合性
    应用范围
    • 9
    • 7
    • 4
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    Protein G affinity chromatography
    免疫原
    A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
    克隆位点
    CFTR-1643
    亚型
    IgG2b
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CFTR / Cystic Fibrosis Transmembrane Regulator
    背景
    Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
    基因ID
    1080
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