Recombinant CFTR / Cystic Fibrosis Transmembrane Regulator 抗体
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Quick Overview for Recombinant CFTR / Cystic Fibrosis Transmembrane Regulator 抗体 (ABIN5707642)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant CFTR Antibody / Rabbit Monoclonal (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- A recombinant human partial protein was used as the immunogen for this recombinant CFTR antibody.
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亚型
- IgG, kappa
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anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody
Carrier-free 适用: 人 IHC (p), FACS 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibodyCarrier-free 适用: 人 IHC (p) 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), FACS 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p) 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibodyCarrier-free 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibodyCarrier-free 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人 IHC (p) 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人 IHC (p) 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
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应用备注
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Optimal dilution of the recombinant CFTR antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CFTR / Cystic Fibrosis Transmembrane Regulator
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背景
- Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride and thiocyanate ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (spermatic cord) and epididymis appear to result from abnormal intraluminal secretions, causing congenital absence of the vas deferens and male infertility. [Wiki]
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UniProt
- P13569
抗原
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