PMEPA1 抗体
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- 抗原 See all PMEPA1 抗体
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PMEPA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 免疫原
- prostate transmembrane protein, androgen induced 1
- 亚型
- IgG
- Top Product
- Discover our top product PMEPA1 Primary Antibody
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anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibody
PMEPA1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PMEPA1-2696 unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PMEPA1-2697 unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 181-280) antibodyPMEPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 173-252) antibodyPMEPA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 21-120) antibodyPMEPA1 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 1268-1341) antibodyPMEPA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) antibodyPMEPA1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) (AA 101-150) antibodyPMEPA1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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L02 cells were subjected to SDS PAGE followed by western blot with FNab06569( PMEPA1 Antibody) at dilution of 1:600
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
- 别名
- PMEPA1 (PMEPA1 产品)
- 别名
- Tmepai antibody, PMEPA1 antibody, TMEPAI antibody, zgc:92731 antibody, tmepai antibody, STAG1 antibody, 2210418I02Rik antibody, AW455466 antibody, Erg1.2 antibody, N4wbp4 antibody, Stag1 antibody, prostate transmembrane protein, androgen induced 1 antibody, prostate transmembrane protein, androgen induced 1 L homeolog antibody, Pmepa1 antibody, PMEPA1 antibody, pmepa1 antibody, pmepa1.L antibody
- 背景
- Synonyms:STAG1, TMEPAI Background:Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal(PubMed:20129061, PubMed:24627487). Also involved in down-regulation of the androgen receptor(AR), enhancing ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4(PubMed:18703514).
- 基因ID
- 56937
- UniProt
- Q969W9
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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