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PMEPA1 抗体 (AA 181-280)

PMEPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A12 unconjugated
产品编号 ABIN566055
发货至: 中国
  • 抗原 See all PMEPA1 抗体
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-280
    适用
    • 19
    • 3
    • 2
    宿主
    • 13
    • 6
    小鼠
    克隆类型
    • 12
    • 7
    单克隆
    标记
    • 17
    • 1
    • 1
    This PMEPA1 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Mouse monoclonal antibody raised against a partial recombinant TMEPAI.
    序列
    NRTIFDSDLM DSARLGGPCP PSSNSGISAT CYGSGGRMEG PPPTYSEVIG HYPGSSFQHQ QSSGPPSLLE GTRLHHTHIA PLESAAIWSK EKDKQKGHPL
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    TMEPAI (AAH15918, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    2A12
    亚型
    IgG2a
    Top Product
    Discover our top product PMEPA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ó hAinmhire, Quartuccio, Cheng, Ahmed, King, Burdette: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).

    Singha, Pandeswara, Geng, Lan, Venkatachalam, Saikumar: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." in: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).

    Costea, Hills, Osman, Thurlow, Kalna, Huang, Pena Murillo, Parajuli, Suliman, Kulasekara, Johannessen, Partridge: "Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma." in: Cancer research, Vol. 73, Issue 13, pp. 3888-901, (2013) (PubMed).

    Hu, He, Wang, Yuan, Liu, Ji, Song: "TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways." in: Carcinogenesis, Vol. 34, Issue 8, pp. 1764-72, (2013) (PubMed).

    Hirokawa, Takagi, Uchida, Kozuka, Yoneda, Watanabe, Shiraishi: "High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone." in: Cellular & molecular biology letters, Vol. 12, Issue 3, pp. 370-7, (2012) (PubMed).

    Watanabe, Itoh, Goto, Ohnishi, Inamitsu, Itoh, Satoh, Wiercinska, Yang, Shi, Tanaka, Nakano, Mommaas, Shibuya, Ten Dijke, Kato: "TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling." in: Molecular cell, Vol. 37, Issue 1, pp. 123-34, (2010) (PubMed).

    Singha, Yeh, Venkatachalam, Saikumar: "Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer." in: Cancer research, Vol. 70, Issue 15, pp. 6377-83, (2010) (PubMed).

    Li, Xu, Masuda, Raymundo, McLeod, Dobi, Srivastava: "A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28988-95, (2008) (PubMed).

  • 抗原
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    别名
    PMEPA1 (PMEPA1 产品)
    别名
    Tmepai antibody, PMEPA1 antibody, TMEPAI antibody, zgc:92731 antibody, tmepai antibody, STAG1 antibody, 2210418I02Rik antibody, AW455466 antibody, Erg1.2 antibody, N4wbp4 antibody, Stag1 antibody, prostate transmembrane protein, androgen induced 1 antibody, prostate transmembrane protein, androgen induced 1 L homeolog antibody, Pmepa1 antibody, PMEPA1 antibody, pmepa1 antibody, pmepa1.L antibody
    背景
    Full Gene Name: prostate transmembrane protein, androgen induced 1
    Synonyms: STAG1,TMEPAI
    基因ID
    56937
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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