USP5 抗体
-
- 抗原 See all USP5 抗体
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This USP5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 免疫原
- ubiquitin specific peptidase 5 (isopeptidase T)
- 亚型
- IgG1
- Top Product
- Discover our top product USP5 Primary Antibody
-
-
- 应用备注
- WB : 1:500-1:5000
- 说明
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09341( USP5 Antibody) at dilution of 1:1000
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
-
- 抗原
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
- 别名
- USP5 (USP5 产品)
- 别名
- ISOT antibody, AA407472 antibody, ISOT-1 antibody, Ucht antibody, ubiquitin specific peptidase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5, putative antibody, ubiquitin specific protease 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody, USP5 antibody, CNH02890 antibody, EHI_049940 antibody, CC1G_12961 antibody, MCYG_01862 antibody, CGB_L3600C antibody, PY00546 antibody, Usp5 antibody
- 背景
- Synonyms:Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 Background:Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
- 分子量
- 93kDa
- 基因ID
- 8078
- UniProt
- P45974
-