USP5 产品
(Ubiquitin Specific Peptidase 5 (USP5))
Categories
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010].
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Featured USP5 Categories
Recommended USP5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p)
Validations
- (9)
Cat. No.
ABIN1501693
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN1683231
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN2856099
Quantity
100 μL
Datasheet
Datasheet
Recommended USP5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232800
Quantity
96 tests
Datasheet
Datasheet
Recommended USP5 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125597
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324831
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324833
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our USP5 Products
: "Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells." in: PLoS ONE, Vol. 8, Issue 12, pp. e80931, (2013) (PubMed).: "Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini." in: The Journal of biological chemistry, Vol. 287, Issue 4, pp. 2317-27, (2012) (PubMed).
: "Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme." in: Chemistry & biology, Vol. 19, Issue 4, pp. 467-77, (2012) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2)." in: FEBS letters, Vol. 376, Issue 3, pp. 233-7, (1996) (PubMed).
: "A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro." in: FEBS letters, Vol. 359, Issue 1, pp. 73-7, (1995) (PubMed).
Synonyms and alternative names related to USP5
ubiquitin specific peptidase 5 (USP5), ubiquitin carboxyl-terminal hydrolase 5 (CNH02890), ubiquitin carboxyl-terminal hydrolase 5 (EHI_049940), ubiquitin carboxyl-terminal hydrolase 5 (CC1G_12961), ubiquitin carboxyl-terminal hydrolase 5 (MCYG_01862), ubiquitin carboxyl-terminal hydrolase 5, putative (CGB_L3600C), ubiquitin specific protease 5 (PY00546), ubiquitin specific peptidase 5 (isopeptidase T) (Usp5), ubiquitin specific peptidase 5 (Usp5), AA407472, ISOT, ISOT-1, UchtProtein level used designations for USP5
- ubiquitin carboxyl-terminal hydrolase 5
- Ubiquitin isopeptidase T
- ubiquitin specific peptidase 5 (isopeptidase T) isoform 1
- ubiquitin specific peptidase 5 (isopeptidase T) isoform 2
- ubiquitin specific protease 5
- ubiquitin specific peptidase 5
- deubiquitinating enzyme 5
- isopeptidase T
- ubiquitin isopeptidase T
- ubiquitin specific protease 5 (isopeptidase T)
- ubiquitin thioesterase 5
- ubiquitin thiolesterase 5
- ubiquitin-specific protease-5 (ubiquitin isopeptidase T)
- ubiquitin-specific-processing protease 5
- ubiquitin carboxy terminal hydrolase T
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