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USP4 产品

(Ubiquitin Specific Peptidase 4 (USP4))

Categories

The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured USP4 Categories

USP4 抗体

High quality antibodies with extensive validation data.

USP4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended USP4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7174328
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2855588
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Horse, Human, Monkey, Pig, Rabbit
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN213585
Quantity 50 μg
Datasheet Datasheet

Recommended USP4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1324801
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324803
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3096198
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our USP4 Products

Zhang, Berger, Yang, Lu: "USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1." in: The EMBO journal, Vol. 30, Issue 11, pp. 2177-89, (2011) (PubMed).

Yang, Xia, Hermance, Mabb, Simonson, Morrissey, Gandhi, Munson, Miyamoto, Kelliher: "A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2774-86, (2011) (PubMed).

Song, Werner, Neubauer, Stegmeier, Aspden, Rio, Harper, Elledge, Kirschner, Rape: "The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome." in: Genes & development, Vol. 24, Issue 13, pp. 1434-47, (2010) (PubMed).

Laurell, Velázquez-Fernández, Lindsten, Juhlin, Enberg, Geli, Höög, Kjellman, Lundeberg, Hamberger, Larsson, Nilsson, Bäckdahl: "Transcriptional profiling enables molecular classification of adrenocortical tumours." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 141-52, (2009) (PubMed).

Soboleva, Jans, Johnson-Saliba, Baker: "Nuclear-cytoplasmic shuttling of the oncogenic mouse UNP/USP4 deubiquitylating enzyme." in: The Journal of biological chemistry, Vol. 280, Issue 1, pp. 745-52, (2004) (PubMed).

Blanchette, Gilchrist, Baker, Gray: "Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130." in: Oncogene, Vol. 20, Issue 39, pp. 5533-7, (2001) (PubMed).

Synonyms and alternative names related to USP4

ubiquitin specific peptidase 4 (USP4), ubiquitin specific peptidase 4 (proto-oncogene) (Usp4), ubiquitin specific peptidase 4 (Usp4), F730026I20Rik, mKIAA4155, UNP, Unp, Unph

Protein level used designations for USP4

  • ubiquitin specific protease 4
  • deubiquitinating enzyme 4
  • ubiquitin carboxyl-terminal esterase 4
  • ubiquitin carboxyl-terminal hydrolase 4
  • ubiquitin specific protease 4 (proto-oncogene)
  • ubiquitin thioesterase 4
  • ubiquitin thiolesterase 4
  • ubiquitin-specific processing protease 4
  • ubiquitous nuclear protein homolog
  • ubiquitin-specific-processing protease 4
  • ubiquitous nuclear protein
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