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USP22 产品

(Ubiquitin Specific Peptidase 22 (USP22))

Categories

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

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Featured USP22 Categories

USP22 抗体

High quality antibodies with extensive validation data.

USP22 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended USP22 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN7271150
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (4)
Cat. No. ABIN2787647
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7174288
Quantity 100 μg
Datasheet Datasheet

Recommended USP22 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6223780
Quantity 96 tests
Datasheet Datasheet

Recommended USP22 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125591
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3075103
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3122439
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our USP22 Products

McCann, Vasilevskaya, Poudel Neupane, Shafi, McNair, Dylgjeri, Mandigo, Schiewer, Schrecengost, Gallagher, Stanek, McMahon, Berman-Booty, Ostrander, Knudsen: "USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair." in: Cancer research, (2019) (PubMed).

Kim, Hong, Park, Shin, Yoo, Jeon, Chung: "Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3664-3676, (2017) (PubMed).

Xiong, Li, He, Zeng, Zhang, He: "lncRNA HULC promotes the growth of hepatocellular carcinoma cells via stabilizing COX-2 protein." in: Biochemical and biophysical research communications, Vol. 490, Issue 3, pp. 693-699, (2017) (PubMed).

Hong, Lee, Chung: "Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination." in: Journal of cellular physiology, Vol. 230, Issue 7, pp. 1651-60, (2015) (PubMed).

Wang, Zhu, Guo, Wang, Yang: "Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma." in: Human pathology, Vol. 46, Issue 7, pp. 1006-14, (2015) (PubMed).

Vijayalingam, Subramanian, Zhao, Chinnadurai: "The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC." in: Journal of virology, Vol. 90, Issue 2, pp. 1070-9, (2015) (PubMed).

Xiao, Tian, Yang, Hu, Xie, Mei, Ding: "USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer." in: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 703-8, (2015) (PubMed).

Schrecengost, Dean, Goodwin, Schiewer, Urban, Stanek, Sussman, Hicks, Birbe, Draganova-Tacheva, Visakorpi, DeMarzo, McMahon, Knudsen: "USP22 regulates oncogenic signaling pathways to drive lethal cancer progression." in: Cancer research, Vol. 74, Issue 1, pp. 272-86, (2014) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." in: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).

Synonyms and alternative names related to USP22

ubiquitin specific peptidase 22 (USP22), ubiquitin specific peptidase 22 (Usp22), ubiquitin specific peptidase 22 (usp22), ubiquitin specific peptidase 22 S homeolog (usp22.S), AI427806, USP3L, usp3l, usp22, usp22 b, usp22-a, usp22-B, zgc:136342

Protein level used designations for USP22

  • deubiquitinating enzyme 22
  • ubiquitin carboxyl-terminal hydrolase 22
  • ubiquitin specific protease 22
  • ubiquitin thioesterase 22
  • ubiquitin thiolesterase 22
  • ubiquitin-specific processing protease 22
  • ubiquitin-specific-processing protease 22
  • ubiquitin specific peptidase 22
  • ubiquitin carboxyl-terminal hydrolase 22-like
  • Deubiquitinating enzyme 22-B
  • Ubiquitin thioesterase 22-B
  • Ubiquitin-specific-processing protease 22-B
  • deubiquitinating enzyme 22 B
  • ubiquitin carboxyl-terminal hydrolase 22-B
  • ubiquitin specific peptidase 22 b
  • ubiquitin thioesterase 22 B
  • ubiquitin thiolesterase 22-B
  • ubiquitin-specific-processing protease 22 B
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