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USP22 抗体 (C-Term)

USP22 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4359 unconjugated
产品编号 ABIN388914
发货至: 中国
  • 抗原 See all USP22 抗体
    USP22 (Ubiquitin Specific Peptidase 22 (USP22))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 351-380, C-Term
    适用
    • 64
    • 29
    • 17
    • 16
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 62
    • 2
    克隆类型
    • 52
    • 12
    多克隆
    标记
    • 25
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP22 antibody is un-conjugated
    应用范围
    • 45
    • 21
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    X, B, Zf, M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This USP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the C-terminal region of human USP22.
    克隆位点
    RB4359
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP22 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Xiong, Li, He, Zeng, Zhang, He: "lncRNA HULC promotes the growth of hepatocellular carcinoma cells via stabilizing COX-2 protein." in: Biochemical and biophysical research communications, Vol. 490, Issue 3, pp. 693-699, (2017) (PubMed).

    Wang, Zhu, Guo, Wang, Yang: "Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma." in: Human pathology, Vol. 46, Issue 7, pp. 1006-14, (2015) (PubMed).

  • 抗原
    USP22 (Ubiquitin Specific Peptidase 22 (USP22))
    别名
    USP22 (USP22 产品)
    别名
    USP3L antibody, AI427806 antibody, zgc:136342 antibody, usp22 antibody, usp22 b antibody, usp22-B antibody, usp22-a antibody, usp3l antibody, ubiquitin specific peptidase 22 antibody, ubiquitin specific peptidase 22 S homeolog antibody, USP22 antibody, Usp22 antibody, usp22 antibody, usp22.S antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    59961
    基因ID
    23326
    NCBI登录号
    NP_056091
    UniProt
    Q9UPT9
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