USP18 产品
(Ubiquitin Specific Peptidase 18 (USP18))
Categories
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011].
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Featured USP18 Categories
USP18 抗体
High quality antibodies with extensive validation data.
USP18 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
USP18 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended USP18 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (6)
Cat. No.
ABIN7271145
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC
Validations
- (4)
Cat. No.
ABIN7076108
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (4)
Cat. No.
ABIN7174583
Quantity
100 μg
Datasheet
Datasheet
Recommended USP18 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971043
Quantity
96 tests
Datasheet
Datasheet
Recommended USP18 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125590
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324763
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324762
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our USP18 Products
: "Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18." in: Alcoholism, clinical and experimental research, Vol. 40, Issue 11, pp. 2329-2338, (2016) (PubMed).Synonyms and alternative names related to USP18
ubiquitin specific peptidase 18 (USP18), ubiquitin specific peptidase 18 (Usp18), 1110058H21Rik, AW047653, bubp43, ISG43, UBP, Ubp15, UBP43, USP18, USP41Protein level used designations for USP18
- 43 kDa ISG15-specific protease
- ISG15-specific-processing protease
- hUBP43
- ubiquitin specific protease 18
- ubl carboxyl-terminal hydrolase 18
- ubl thioesterase 18
- ubl thiolesterase 18
- ubiquitin specific peptidase 18
- ubiquitin specific protease 15
- interferon-stimulated gene 43
- ubiquitin-specific protease 18
- ubiquitin specific peptidase 41
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