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USP18 抗体 (AA 200-300)

USP18 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271145
发货至: 中国
  • 抗原 See all USP18 抗体
    USP18 (Ubiquitin Specific Peptidase 18 (USP18))
    抗原表位
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    AA 200-300
    适用
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    • 3
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP18 antibody is un-conjugated
    应用范围
    • 16
    • 10
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    原理
    USP18 Rabbit pAb
    序列
    DVDSKPLKTL EDALHCFFQP RELSSKSKCF CENCGKKTRG KQVLKLTHLP QTLTIHLMRF SIRNSQTRKI CHSLYFPQSL DFSQILPMKR ESCDAEEQSG G
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human USP18 (NP_059110.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    USP18 (Ubiquitin Specific Peptidase 18 (USP18))
    别名
    USP18 (USP18 产品)
    别名
    ISG43 antibody, UBP43 antibody, bubp43 antibody, 1110058H21Rik antibody, AW047653 antibody, Ubp15 antibody, UBP antibody, USP18 antibody, USP41 antibody, ubiquitin specific peptidase 18 antibody, USP18 antibody, Usp18 antibody
    背景
    The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15.,USP18,ISG43,UBP43,PTORCH2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP18
    分子量
    43kDa
    基因ID
    11274
    UniProt
    Q9UMW8
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