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Notch1 抗体

NOTCH1 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5704034
发货至: 中国
  • 抗原 See all Notch1 (NOTCH1) 抗体
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This Notch1 antibody is un-conjugated
    应用范围
    • 91
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    Notch gene homolog 1 (Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product NOTCH1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    别名
    Notch1 (NOTCH1 产品)
    别名
    notch1 antibody, NOTCH1 antibody, hn1 antibody, tan1 antibody, notch antibody, xotch antibody, xnotch antibody, notch-1 antibody, xnotch1 antibody, TAN1 antibody, hN1 antibody, 9930111A19Rik antibody, Mis6 antibody, N1 antibody, Tan1 antibody, lin-12 antibody, NOTCH antibody, Xotch antibody, notch1-a antibody, notch 1 antibody, fibropellin-1 antibody, Notch homolog 1, translocation-associated (Drosophila) antibody, Notch homolog 1, translocation-associated antibody, notch 1 S homeolog antibody, notch1 antibody, LOC100631526 antibody, NOTCH1 antibody, Notch1 antibody, notch1.S antibody
    背景
    Synonyms:AOS5, AOVD1, hN1, TAN1 Background:This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.
    分子量
    270-300 kDa
    基因ID
    4851
    UniProt
    P46531
    途径
    Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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