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CHEK1 抗体

This anti-CHEK1 antibody is a 兔 多克隆 antibody detecting CHEK1 in WB, ELISA, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5703772
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN5703772)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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人, 小鼠, 大鼠

宿主

  • 193
  • 12
  • 5
  • 5

克隆类型

  • 188
  • 28
多克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 免疫原

    CHK1 checkpoint homolog (S. pombe)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    Chk1

    背景

    Synonyms: Background:The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

    分子量

    50-55 kDa

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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