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CSK 抗体

CSK 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5702649
发货至: 中国
  • 抗原 See all CSK 抗体
    CSK (C-Src tyrosine Kinase (CSK))
    适用
    • 111
    • 57
    • 45
    • 4
    • 4
    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 100
    • 10
    • 3
    克隆类型
    • 100
    • 12
    多克隆
    标记
    • 53
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    • 7
    • 5
    • 4
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    • 3
    • 3
    • 3
    • 3
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    This CSK antibody is un-conjugated
    应用范围
    • 102
    • 49
    • 26
    • 26
    • 16
    • 15
    • 13
    • 9
    • 7
    • 6
    • 6
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    免疫原
    c-src tyrosine kinase
    亚型
    IgG
    Top Product
    Discover our top product CSK Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    HL-60 cells were subjected to SDS PAGE followed by western blot with FNab02016(CSK antibody) at dilution of 1:800

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    CSK (C-Src tyrosine Kinase (CSK))
    别名
    CSK (CSK 产品)
    别名
    AW212630 antibody, C-terminal Src kinase antibody, c-src tyrosine kinase antibody, CSK, non-receptor tyrosine kinase antibody, CSK antibody, Csk antibody
    背景
    Synonyms: Background:Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases(SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor(TCR) and B-cell receptor(BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
    分子量
    50 kDa
    基因ID
    1445
    UniProt
    P41240
    途径
    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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