CSK 抗体
(C-Src tyrosine Kinase (CSK))
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CSK 抗体 (AA 1-100) | 人 | 小鼠 Monoclonal |
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| CSK 抗体 | 人, 小鼠, 大鼠, 猴 | 小鼠 Monoclonal |
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| CSK 抗体 | 人 | 兔 Monoclonal |
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| CSK 抗体 (C-Term) | 人 | 山羊 Polyclonal |
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| Recombinant CSK 抗体 | 人 | 兔 Monoclonal |
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| CSK 抗体 (AA 2-204) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CSK 抗体 (N-Term) | 小鼠 | 兔 Polyclonal |
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| CSK 抗体 (AA 241-450) | 人 | 兔 Polyclonal |
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| CSK 抗体 (AA 1-200) | 人 | 兔 Polyclonal |
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| CSK 抗体 (AA 325-416) | 人 | 兔 Polyclonal |
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| CSK 抗体 (AA 330-450) | 人, 小鼠 | 小鼠 Monoclonal |
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| CSK 抗体 (AA 1-450) | 人 | 小鼠 Monoclonal |
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| CSK 抗体 (Ser280) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CSK 抗体 (AA 243-438) | 人 | 兔 Polyclonal |
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| CSK 抗体 (pSer364) | 人 | 兔 Polyclonal |
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| CSK 抗体 (AA 301-400) | 人 | 兔 Polyclonal |
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| CSK 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CSK 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CSK 抗体 (AA 164-197) | 人 | 兔 Polyclonal |
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| CSK 抗体 (N-Term) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- ISt (Immunostaining: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- RNAi (RNA Interference: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3A3
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
3 references - 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5F3
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB1920
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-204
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB50568
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 67-101, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 241-450
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-200
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 325-416
Primary Antibody
- ICC (Immunocytochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- CSK-04
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 330-450
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AT7C6
- 标记
- unconjugated
- 抗体亚型
- IgG2b kappa
- 抗原表位
- AA 1-450
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Ser280
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 243-438
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer364
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB50568
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 398-431, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB50498
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 17-51, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB50499
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 164-197
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB33742
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 33-61, N-Term
Latest Publications for our CSK 抗体
: "Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase." in: Scientific reports, Vol. 3, pp. 926, (2013) (PubMed).
: "Beta-catenin inhibits melanocyte migration but induces melanoma metastasis." in: Oncogene, Vol. 32, Issue 17, pp. 2230-8, (2013) (PubMed).
: "Genome-wide association study of blood pressure and hypertension. ..." in: Nature genetics, Vol. 41, Issue 6, pp. 677-87, (2010) (PubMed).
: "Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study." in: Journal of hypertension, Vol. 29, Issue 1, pp. 62-9, (2010) (PubMed).
: "A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias." in: Leukemia research, Vol. 33, Issue 9, pp. e168-9, (2009) (PubMed).
: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).
: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).
: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).
: "The COOH-terminal Src kinase Csk is a tumor antigen in human carcinoma." in: Cancer research, Vol. 61, Issue 4, pp. 1415-20, (2001) (PubMed).
: "Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of ..." in: The Journal of biological chemistry, Vol. 274, Issue 4, pp. 2291-7, (1999) (PubMed).
: "Beta-catenin inhibits melanocyte migration but induces melanoma metastasis." in: Oncogene, Vol. 32, Issue 17, pp. 2230-8, (2013) (PubMed).
: "Genome-wide association study of blood pressure and hypertension. ..." in: Nature genetics, Vol. 41, Issue 6, pp. 677-87, (2010) (PubMed).
: "Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study." in: Journal of hypertension, Vol. 29, Issue 1, pp. 62-9, (2010) (PubMed).
: "A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias." in: Leukemia research, Vol. 33, Issue 9, pp. e168-9, (2009) (PubMed).
: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).
: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).
: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).
: "The COOH-terminal Src kinase Csk is a tumor antigen in human carcinoma." in: Cancer research, Vol. 61, Issue 4, pp. 1415-20, (2001) (PubMed).
: "Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of ..." in: The Journal of biological chemistry, Vol. 274, Issue 4, pp. 2291-7, (1999) (PubMed).
Aliases for CSK 抗体
C-terminal Src kinase (CSK) 抗体c-src tyrosine kinase (Csk) 抗体
C-terminal Src kinase (Csk) 抗体
c-src tyrosine kinase (CSK) 抗体
CSK, non-receptor tyrosine kinase (CSK) 抗体
AW212630 抗体
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