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APC 抗体

APC 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5702078
发货至: 中国
  • 抗原 See all APC 抗体
    APC (Adenomatous Polyposis Coli (APC))
    适用
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This APC antibody is un-conjugated
    应用范围
    • 48
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    Immunohistochemistry (IHC), ELISA
    免疫原
    adenomatous polyposis coli
    亚型
    IgG
    Top Product
    Discover our top product APC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    APC (Adenomatous Polyposis Coli (APC))
    别名
    APC (APC 产品)
    别名
    dp2 antibody, dp3 antibody, fap antibody, fpc antibody, xapc antibody, dp2.5 antibody, AI047805 antibody, AU020952 antibody, AW124434 antibody, CC1 antibody, Min antibody, mAPC antibody, BTPS2 antibody, DP2 antibody, DP2.5 antibody, DP3 antibody, GS antibody, PPP1R46 antibody, RATAPC antibody, APC1 antibody, APC, WNT signaling pathway regulator antibody, adenomatous polyposis coli antibody, adenomatous polyposis coli protein, putative antibody, adenomatosis polyposis coli antibody, adenomatous polyposis coli L homeolog antibody, APC antibody, apc antibody, Smp_139190 antibody, Apc antibody, apc.L antibody
    背景
    Synonyms:adenomatous polyposis coli, APC, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, DP3, GS, Protein APC Background:Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor(HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
    基因ID
    324
    UniProt
    P25054
    途径
    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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