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APC 抗体

(Adenomatous Polyposis Coli (APC))
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
APC 抗体 APC 抗体 APC 抗体 (ABIN7260669)

APC 适用: 人, 小鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated

APC 抗体  (pSer2054) APC 抗体  (pSer2054) APC 抗体 (pSer2054) (ABIN6255083)

APC 适用: 人, 小鼠 ELISA, ICC, IF, IHC, WB 宿主: 兔 Polyclonal unconjugated

APC 抗体  (Internal Region) APC 抗体  (Internal Region) APC 抗体 (Internal Region) (ABIN6259974)

APC 适用: 人, 小鼠, 大鼠 ELISA, ICC, IF, IHC, WB 宿主: 兔 Polyclonal unconjugated

APC 抗体 by 适用

Find APC 抗体 for a variety of species such as anti-Human APC, anti-Mouse APC, anti-Rat APC. The species listed below are among those available. Click on a link to go to the corresponding products.

APC 抗体 by 应用范围

Find APC 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

APC 抗体 by 抗体来源

Find APC 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

APC 抗体 by 抗原表位

Find APC 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APC 抗体 by 克隆形成能力

Find available monoclonal or polyclonal APC 抗体. Click on a link to go to the corresponding products.

APC 抗体 by 克隆

Find APC 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

APC 抗体 by 标记

Find APC 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Cow, Human, Pig, Rat
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2704484
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, PLA, ELISA, WB
Validations
  • (3)
Cat. No. ABIN559888
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN7184577
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7127341
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN3183309
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7244711
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (2)
Cat. No. ABIN7265452
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rabbit
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN2972835
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1531521
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1533213
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (2)
Cat. No. ABIN702550
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application PLA, WB
Validations
  • (2)
Cat. No. ABIN513388
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3029869
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IF, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN265313
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application Coat, ELISA, FACS, IF, WB
Validations
  • (1)
Cat. No. ABIN6939658
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our APC 抗体

Nakayama, Abe, Morimoto, Iida, Okabe, Sakimura, Hashimoto: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." in: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).

Liu, Song, Luan, Sun, Bai, Wang, Li, Zhang, Feng, Du: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).

Liu, Tackmann, Yang, Zhang: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." in: Oncogene, (2016) (PubMed).

Onuma, Ochiai, Orihashi, Takahashi, Imai, Nakagama, Hippo: "Genetic reconstitution of tumorigenesis in primary intestinal cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).

Hendriksen, Jansen, Brown, van der Velde, van Ham, Galjart, Offerhaus, Fagotto, Fornerod: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." in: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).

Abutaily, Collins, Roche: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).

Aliases for APC 抗体

APC, WNT signaling pathway regulator (APC) 抗体
adenomatous polyposis coli (apc) 抗体
adenomatous polyposis coli protein, putative (Smp_139190) 抗体
adenomatosis polyposis coli (Apc) 抗体
APC, WNT signaling pathway regulator (Apc) 抗体
adenomatous polyposis coli L homeolog (apc.L) 抗体
AI047805 抗体
APC1 抗体
AU020952 抗体
AW124434 抗体
BTPS2 抗体
CC1 抗体
dp2 抗体
DP2 抗体
dp2.5 抗体
DP2.5 抗体
dp3 抗体
DP3 抗体
fap 抗体
fpc 抗体
GS 抗体
mAPC 抗体
Min 抗体
PPP1R46 抗体
RATAPC 抗体
xapc 抗体
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