APC 抗体
(Adenomatous Polyposis Coli (APC))
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| APC 抗体 (AA 2636-2845) | 小鼠 | 兔 Polyclonal |
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| APC 抗体 (AA 2544-2843) | 人 | 兔 Polyclonal |
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| APC 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| APC 抗体 (AA 2634-2842) | 大鼠 | 兔 Polyclonal |
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| APC 抗体 (AA 2744-2843) | 人 | 小鼠 Monoclonal |
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| APC 抗体 (AA 2751-2843) | 人 | 兔 Polyclonal |
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| APC 抗体 (AA 1-50) | 人 | 兔 Polyclonal |
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| APC 抗体 (AA 2644-2843) | 人 | 小鼠 Monoclonal |
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| APC 抗体 | 人 | 兔 Monoclonal |
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| Recombinant APC 抗体 | 人 | 兔 Monoclonal |
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| APC 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| APC 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant APC 抗体 | 人 | 兔 Monoclonal |
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| APC 抗体 (AA 1-2843) | 人 | 兔 Polyclonal |
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| APC 抗体 (AA 1-433) | 人 | 小鼠 Monoclonal |
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| APC 抗体 (AA 1148-1176) | 小鼠 | 兔 Polyclonal |
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| APC 抗体 (AA 75-125) | 人 | 兔 Polyclonal |
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| APC 抗体 (AA 1-50) | 人 | 兔 Polyclonal |
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| APC 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| APC 抗体 (AA 2794-2843) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2636-2845
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2544-2843
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
1 reference - 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2634-2842
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3E2
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 2744-2843
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2751-2843
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-50
Primary Antibody
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1F7G2
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 2644-2843
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 5F2
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 24GB3260
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-2843
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- ALi 12-28
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 1-433
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB37442
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 1148-1176
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 75-125
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-50
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2794-2843
Latest Publications for our APC 抗体
: "Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway." in: Journal of the American Heart Association, Vol. 13, Issue 19, pp. e036054, (2024) (PubMed).
: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." in: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).
: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).
: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." in: Oncogene, (2016) (PubMed).
: "Genetic reconstitution of tumorigenesis in primary intestinal cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).
: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." in: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).
: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).
: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." in: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).
: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).
: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." in: Oncogene, (2016) (PubMed).
: "Genetic reconstitution of tumorigenesis in primary intestinal cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).
: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." in: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).
: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).
Aliases for APC 抗体
APC, WNT signaling pathway regulator (APC) 抗体adenomatous polyposis coli (apc) 抗体
adenomatous polyposis coli protein, putative (Smp_139190) 抗体
adenomatosis polyposis coli (Apc) 抗体
APC, WNT signaling pathway regulator (Apc) 抗体
adenomatous polyposis coli L homeolog (apc.L) 抗体
AI047805 抗体
APC1 抗体
AU020952 抗体
AW124434 抗体
BTPS2 抗体
CC1 抗体
dp2 抗体
DP2 抗体
dp2.5 抗体
DP2.5 抗体
dp3 抗体
DP3 抗体
fap 抗体
fpc 抗体
GS 抗体
mAPC 抗体
Min 抗体
PPP1R46 抗体
RATAPC 抗体
xapc 抗体
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