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APEX2 抗体

(APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
APEX2 抗体  (Center) APEX2 抗体  (Center) APEX2 抗体 (Center) (ABIN2157746)

APEX2 适用: 人 FACS, IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

APEX2 抗体 APEX2 抗体 APEX2 抗体 (ABIN3003990)

APEX2 适用: 人 FACS, IF/ICC, IHC, WB 宿主: 兔 Polyclonal unconjugated

APEX2 抗体  (AA 1-518) APEX2 抗体  (AA 1-518) APEX2 抗体 (AA 1-518) (ABIN525954)

APEX2 适用: 人 IF, WB 宿主: 小鼠 Polyclonal unconjugated

APEX2 抗体 by 适用

Find APEX2 抗体 for a variety of species such as anti-Human APEX2, anti-Rat APEX2, anti-Mouse APEX2. The species listed below are among those available. Click on a link to go to the corresponding products.

APEX2 抗体 by 应用范围

Find APEX2 抗体 validated for a specific application such as WB, IHC, ELISA, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

APEX2 抗体 by 抗体来源

Find APEX2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

APEX2 抗体 by 抗原表位

Find APEX2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APEX2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal APEX2 抗体. Click on a link to go to the corresponding products.

APEX2 抗体 by 克隆

Find APEX2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

APEX2 抗体 by 标记

Find APEX2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APEX2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB
Validations
  • (1)
Cat. No. ABIN5518737
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
Cat. No. ABIN718481
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7265632
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
Cat. No. ABIN2686181
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN5515372
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC, WB
Validations
Cat. No. ABIN2793578
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN718483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC (p), WB
Validations
Cat. No. ABIN652924
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718485
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718484
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718487
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718488
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718486
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN718490
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN882986
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our APEX2 抗体

Mengwasser, Adeyemi, Leng, Choi, Clairmont, DAndrea, Elledge: "Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets." in: Molecular cell, Vol. 73, Issue 5, pp. 885-899.e6, (2019) (PubMed).

Karkhanis, Wang, Tae, Hu, Imbalzano, Sif: "Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1." in: The Journal of biological chemistry, Vol. 287, Issue 35, pp. 29801-14, (2012) (PubMed).

Tsuchimoto, Sakai, Sakumi, Nishioka, Sasaki, Fujiwara, Nakabeppu: "Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen." in: Nucleic acids research, Vol. 29, Issue 11, pp. 2349-60, (2001) (PubMed).

Aliases for APEX2 抗体

apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2) 抗体
apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2) 抗体
APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2) 抗体
apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L) 抗体
APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2) 抗体
apurinic/apyrimidinic endonuclease 2 (Apex2) 抗体
apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2) 抗体
APE2 抗体
ape2 抗体
APEXL2 抗体
apexl2 抗体
C430040P13Rik 抗体
XTH2 抗体
xth2 抗体
zgc:55889 抗体
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