APEX2 抗体 (AA 102-210) (Biotin)
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北京 101111
Quick Overview for APEX2 抗体 (AA 102-210) (Biotin) (ABIN7969257)
抗原
See all APEX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-210
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原理
- Anti-APEX2 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human APEX2 shares 91.7% amino acid (aa) sequence identity with mouse APEX2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human APEX2 recombinant protein (Position: L102-A210). Human APEX2 shares 91.7% amino acid (aa) sequence identity with mouse APEX2.
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亚型
- IgG
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anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 143-171) antibody
APEX2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB23043 unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 1-518) antibodyAPEX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 301-400) antibodyAPEX2 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 102-210) antibodyAPEX2 适用: 人, 小鼠, 大鼠, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) antibodyAPEX2 适用: 人 WB, FACS, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 1-500) antibodyAPEX2 适用: 人 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
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别名
- APEX2
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背景
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Background: APEX2, also called apurinic/apyrimidinic endonuclease like-2, is a member of the apurinic/apyrimidinic (AP) family of endonucleases that initiate the repair of AP sites formed by spontaneous hydrolysis of the N-glycosylic bond, mutagen-induced base release, or damaged-base excision by a DNA repair glycosylase. RT-PCR detected APEX2 expression in HeLa cells, Jurkat cells, and human kidney, brain and fetal brain tissue. The APEX2 gene is mapped to chromosome Xp11.21. APEX2 participates in both nuclear and mitochondrial base excision repair (BER) and it can play a role in processing 3-prime-damaged termini or 3-prime-mismatched nucleotides. Additionally, APEX2 displayed weaker AP site-specific and 3-prime nuclease activities compared to APEX1.
Gene Full Name: apurinic/apyrimidinic endodeoxyribonuclease 2
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基因ID
- 27301
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UniProt
- Q9UBZ4
抗原
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