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FADD 抗体

FADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701779
发货至: 中国
  • 抗原 See all FADD 抗体
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    适用
    • 86
    • 59
    • 19
    • 18
    • 15
    人, 小鼠, 大鼠
    宿主
    • 95
    • 17
    克隆类型
    • 93
    • 19
    多克隆
    标记
    • 64
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FADD antibody is un-conjugated
    应用范围
    • 86
    • 50
    • 31
    • 15
    • 15
    • 12
    • 11
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    免疫原
    Fas (TNFRSF6)-associated via death domain
    亚型
    IgG
    Top Product
    Discover our top product FADD Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab02941( FADD Antibody) at dilution of 1:300

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • Li, Mo, Lei, Li, Fu, Huang, Luo, Zhang: "Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 99, pp. 169-177, (2018) (PubMed).

  • 抗原
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    别名
    FADD (FADD 产品)
    别名
    MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
    背景
    Synonyms:FADD, GIG3, MORT1, Protein FADD Background:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
    分子量
    23 kDa
    基因ID
    8772
    UniProt
    Q13158
    途径
    Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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