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TRAF6 抗体

TRAF6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701257
发货至: 中国
  • 抗原 See all TRAF6 抗体
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    适用
    • 55
    • 31
    • 26
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    人, 小鼠, 大鼠
    宿主
    • 53
    • 4
    • 2
    克隆类型
    • 54
    • 5
    多克隆
    标记
    • 36
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    This TRAF6 antibody is un-conjugated
    应用范围
    • 55
    • 18
    • 13
    • 13
    • 13
    • 10
    • 10
    • 8
    • 6
    • 3
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    免疫原
    TNF receptor-associated factor 6
    亚型
    IgG
    Top Product
    Discover our top product TRAF6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    A431 cells were subjected to SDS PAGE followed by western blot with FNab08921(TRAF6 antibody) at dilution of 1:300

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    别名
    TRAF6 (TRAF6 产品)
    别名
    MGC:3310 antibody, RNF85 antibody, 2310003F17Rik antibody, AI851288 antibody, C630032O20Rik antibody, rnf85 antibody, traf6 antibody, xtraf6 antibody, CG10961 antibody, DTRAF2 antibody, Dmel\\CG10961 antibody, TRAF antibody, TRAF2 antibody, TRAF6 antibody, Traf2 antibody, dTRAF2 antibody, dTRAF6 antibody, dTraf2 antibody, dtraf2 antibody, GB10539 antibody, fi15f02 antibody, wu:fi15f02 antibody, zgc:63704 antibody, TNF receptor associated factor 6 antibody, TNF receptor-associated factor 6 antibody, TNF receptor associated factor 6 L homeolog antibody, TNF-receptor-associated factor 6 antibody, TNF receptor associated factor 6 S homeolog antibody, TRAF6 antibody, Traf6 antibody, traf6.L antibody, traf6 antibody, LOC551819 antibody, traf6.S antibody
    背景
    Synonyms:RING finger protein 85, RNF85, TRAF6 Background:E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells(DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1(AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.
    基因ID
    7189
    UniProt
    Q9Y4K3
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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