TRPV4 抗体
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- 抗原 See all TRPV4 抗体
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPV4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- transient receptor potential cation channel, subfamily V, member 4
- 亚型
- IgG
- Top Product
- Discover our top product TRPV4 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Middle Region) antibody
TRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (3rd Extracellular Loop), (AA 647-662) antibodyTRPV4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Internal Region) antibodyTRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, Hamster, 马 WB, IHC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 853-871), (C-Term), (Intracellular) antibodyTRPV4 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 301-400) antibodyTRPV4 适用: 人, Cow WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 1-230) antibodyTRPV4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (C-Term) antibodyTRPV4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) antibodyTRPV4 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (N-Term) antibodyTRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 461-510) antibodyTRPV4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:200-1:2000,IHC:1:50-1:200
- 说明
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SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab09028(TRPV4 antibody) at dilution of 1:800
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
- 别名
- TRPV4 (TRPV4 产品)
- 别名
- wu:fp52e02 antibody, CMT2C antibody, HMSN2C antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, TRP12 antibody, VRL2 antibody, VROAC antibody, 0610033B08Rik antibody, Trp12 antibody, VR-OAC antibody, VRL-2 antibody, Otrpc4 antibody, Vroac antibody, transient receptor potential cation channel, subfamily V, member 4 antibody, transient receptor potential cation channel subfamily V member 4 antibody, trpv4 antibody, TRPV4 antibody, Trpv4 antibody
- 背景
- Synonyms:Osm 9 like TRP channel 4, OTRPC4, TRP12, TRPV4, VR OAC, VRL 2, VRL2, VROAC Background:Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification(PubMed:18826956, PubMed:18695040). Also activated by heat, low pH , citrate and phorbol esters(PubMed:18826956, PubMed:18695040). Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism(PubMed:12724311, PubMed:18826956). Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers(By similarity). Acts as a regulator of intracellular Ca(2+) in synoviocytes(PubMed:19759329). Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8(PubMed:19759329). Together with PKD2, forms mechano-and thermosensitive channels in cilium(PubMed:18695040). Negatively regulates expression of PPARGC1A, UCP1, oxidative metabolism and respiration in adipocytes(By similarity). Regulates expression of chemokines and cytokines related to proinflammatory pathway in adipocytes(By similarity). Together with AQP5, controls regulatory volume decrease in salivary epithelial cells(By similarity).
- 分子量
- 28kDa
- 基因ID
- 59341
- UniProt
- Q9HBA0
- 途径
- Hormone Transport, Cell-Cell Junction Organization
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