(1 reference)-
- 抗原 See all BNIP3 抗体
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BNIP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 品牌
- Picoband™
- 序列
- KEFLFKHPKR TATLSMRNTS VMKK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for BNIP3 detection. Tested with WB in Human,Mouse,Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence of human BNIP3 (KEFLFKHPKRTATLSMRNTSVMKK).
- Top Product
- Discover our top product BNIP3 Primary Antibody
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibody
BNIP3 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5F7 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibodyBNIP3 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E11F4 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 152-187) antibodyBNIP3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 3-134) antibodyBNIP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) antibodyBNIP3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 215-252) antibodyBNIP3 适用: 人, 小鼠 ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 112-124) antibodyBNIP3 适用: 人 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (C-Term) antibody (FITC)BNIP3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Application Details: Western blot, 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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: "MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling." in: Oncotarget, Vol. 8, Issue 37, pp. 61510-61527, (2017) (PubMed).
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: "MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling." in: Oncotarget, Vol. 8, Issue 37, pp. 61510-61527, (2017) (PubMed).
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- 抗原
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
- 别名
- BNIP3 (BNIP3 产品)
- 别名
- NIP3 antibody, Nip3 antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BNIP3 antibody, Bnip3 antibody
- 背景
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Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Background: The Bcl-2 nineteen kilodalton interacting protein 3 (BNIP3 or NIP3), is a hypoxia-inducible proapoptotic member of the Bcl-2 family that induces cell death by associating with the mitochondria. BNIP3, expressed in skeletal muscle and in the brain at low levels, is primarily localized to the nucleus of glial cells of the normal human brain, as well as in the malignant glioma cell line U251. BNIP3 expression in the cytoplasm increases and localizes with the mitochondria, contributing to induction of cell death. Cellular protein BNIP3 interacts with E1B-19K, BCL-2, BCL-xL, and EBV-BHRF1. BNIP3 contains Bcl-2 homology 3 (BH3) domain and COOH-terminal transmembrane (TM) domain. The BH3 domain of BNIP3 mediates Bcl-2/Bcl-X(L) heterodimerization and confers pro-apoptotic activity, whereas the TM domain is critical for homodimerization, pro-apoptotic function, and mitochondrial targeting.
- UniProt
- Q12983
- 途径
- Autophagy, Brown Fat Cell Differentiation
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