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SYK 抗体 (pTyr323)

SYK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5689842
发货至: 中国
  • 抗原 See all SYK 抗体
    SYK (Spleen tyrosine Kinase (SYK))
    抗原表位
    • 29
    • 22
    • 19
    • 13
    • 10
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
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    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
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    pTyr323
    适用
    • 167
    • 81
    • 51
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    宿主
    • 156
    • 14
    • 3
    克隆类型
    • 159
    • 13
    多克隆
    标记
    • 99
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
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    • 2
    This SYK antibody is un-conjugated
    应用范围
    • 145
    • 83
    • 46
    • 25
    • 22
    • 18
    • 14
    • 14
    • 12
    • 4
    • 4
    • 3
    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous level of syk only when phosphorylated at tyrosine 323.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
    免疫原
    syk (phospho-Tyr323) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y (p) -E- P) derived from Human syk.
    Top Product
    Discover our top product SYK Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    SYK (Spleen tyrosine Kinase (SYK))
    别名
    syk (SYK 产品)
    别名
    p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody
    背景
    Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C γ,dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion
    分子量
    72 kDa
    基因ID
    6850
    NCBI登录号
    NP_001128524
    UniProt
    P43405
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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