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SYK 抗体 (pTyr323)

SYK 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN746258
发货至: 中国
  • 抗原 See all SYK 抗体
    SYK (Spleen tyrosine Kinase (SYK))
    抗原表位
    • 29
    • 21
    • 20
    • 13
    • 10
    • 10
    • 8
    • 8
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    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pTyr323
    适用
    • 170
    • 81
    • 51
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    小鼠
    宿主
    • 157
    • 15
    • 3
    克隆类型
    • 160
    • 14
    多克隆
    标记
    • 101
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
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    • 2
    This SYK antibody is un-conjugated
    应用范围
    • 146
    • 83
    • 46
    • 25
    • 23
    • 19
    • 14
    • 14
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    • 4
    • 4
    • 3
    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr323
    亚型
    IgG
    Top Product
    Discover our top product SYK Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SYK (Spleen tyrosine Kinase (SYK))
    别名
    Syk (SYK 产品)
    别名
    p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody
    背景

    Synonyms: syk Tyr323, Tyrosine-protein kinase SYK Spleen tyrosine kinase [Contains: 72 kDa tyrosine-protein kinase SYK, 40 kDa tyrosine-protein kinase SYK, KSYK_HUMAN.

    Background: Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk, Spleen tyrosine kinase, Tyrosine protein kinase SYK.

    基因ID
    6850
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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