PAK1/2/3 抗体
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- 抗原 See all PAK1/2/3 抗体
- PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK1/2/3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous level of total PAK1/PAK2/PAK3 protein.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- PAK1/PAK2/PAK3 (Ab-423/402/421) antibody was raised against a peptide sequence around aa.421~425/400~404/419~423 (R-S-T-M-V) derived from Human PAK1/PAK2/PAK3.
- Top Product
- Discover our top product PAK1/2/3 Primary Antibody
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anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (Thr402), (Thr421), (Thr423) antibody
PAK1/2/3 适用: 人 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (Thr402), (Thr421), (Thr423) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (pThr423) antibodyPAK1/2/3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (pThr423) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (pSer139), (pSer141), (pSer144) antibodyPAK1/2/3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (pThr423) antibodyPAK1/2/3 适用: 人 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (AA 391-440) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (AA 111-160), (pSer144) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
- 别名
- PAK1 / PAK2 / PAK3 (PAK1/2/3 产品)
- 别名
- X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, pak1.S antibody, PAK1 antibody
- 背景
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
- 分子量
- 61 - 67 (PAK2) 68 - 74 (PAK1/3) kDa
- 基因ID
- 5058, 5062, 5063
- NCBI登录号
- NP_001122092, NP_002568, NP_001121638
- UniProt
- Q13153, Q13177, O75914
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