PAK1/2/3 抗体 (AA 391-440)
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北京 101111
Quick Overview for PAK1/2/3 抗体 (AA 391-440) (ABIN1532384)
抗原
See all PAK1/2/3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-440
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原理
- PAKα/β/γ Antibody
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特异性
- PAKα/β/γ Polyclonal Antibody detects endogenous levels of PAKα/β/γ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PAK1/2/3. AA range:391-440
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
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别名
- PAK1/2/3
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背景
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Synonyms: PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p
Background: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],
Gene Name: PAK1/PAK2/PAK3
Protein Name: Serine/threonine-protein kinase PAK 1
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分子量
- 60 kDa
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基因ID
- 5058, 5062, 5063
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OMIM
- 602590
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UniProt
- Q13153
抗原
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