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PAK1/2/3 抗体 (AA 391-440)

This 兔 多克隆 antibody specifically detects PAK1/2/3 in IHC, WB, ELISA 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1532384
发货至: 中国
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Quick Overview for PAK1/2/3 抗体 (AA 391-440) (ABIN1532384)

抗原

See all PAK1/2/3 抗体
PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

适用

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人, 大鼠, 小鼠

宿主

  • 68
兔

克隆类型

  • 46
  • 22
多克隆

标记

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This PAK1/2/3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 391-440

    原理

    PAKα/β/γ Antibody

    特异性

    PAKα/β/γ Polyclonal Antibody detects endogenous levels of PAKα/β/γ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human PAK1/2/3. AA range:391-440

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

    别名

    PAK1/2/3

    背景

    Synonyms: PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p

    Background: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

    Gene Name: PAK1/PAK2/PAK3

    Protein Name: Serine/threonine-protein kinase PAK 1

    分子量

    60 kDa

    基因ID

    5058, 5062, 5063

    OMIM

    602590

    UniProt

    Q13153
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