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PAK1/2/3 抗体 (pSer139, pSer141, pSer144)

PAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, WB, IHC (p), IF (cc), FACS, IP 宿主: 兔 Monoclonal 7G3 unconjugated
产品编号 ABIN6989928
发货至: 中国
  • 抗原 See all PAK1/2/3 抗体
    PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
    抗原表位
    • 13
    • 11
    • 10
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139, pSer141, pSer144
    适用
    • 34
    • 26
    • 25
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 35
    克隆类型
    • 34
    • 1
    单克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK1/2/3 antibody is un-conjugated
    应用范围
    • 20
    • 19
    • 19
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunoprecipitation (IP)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic phospho-Peptide corresponding to residues surrounding Ser144 of human PAK1.
    克隆位点
    7G3
    亚型
    IgG
    Top Product
    Discover our top product PAK1/2/3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IP(1-2 μg)
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
    别名
    PAK1+PAK2+PAK3 (PAK1/2/3 产品)
    别名
    X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, pak1.S antibody, PAK1 antibody
    背景

    Synonyms: ,

    Background: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

    基因ID
    5063
    UniProt
    O75914
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