电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

BDNF 抗体 (Biotin)

BDNF 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN5688972
发货至: 中国
  • 抗原 See all BDNF 抗体
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    适用
    • 111
    • 56
    • 54
    • 14
    • 10
    • 10
    • 9
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    人, 大鼠, 小鼠
    宿主
    • 108
    • 24
    • 4
    • 3
    • 2
    • 1
    克隆类型
    • 112
    • 29
    多克隆
    标记
    • 80
    • 16
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BDNF antibody is conjugated to Biotin
    应用范围
    • 110
    • 45
    • 45
    • 30
    • 25
    • 24
    • 18
    • 13
    • 13
    • 12
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Anti-hBDNF specific antibody was purified by affinity chromatography and then biotinylated.
    免疫原
    Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hBDNF (human BDNF).
    Top Product
    Discover our top product BDNF Primary Antibody
  • 应用备注
    ELISA:

    To detect hBDNF by direct ELISA (using 100 μ,L/well antibody solution) this antibody can be used at a concentration of 0.15 - 0.30 μ,g/mL. Used in conjunction with compatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinant hBDNF.

    Western Blot:
    To detect hBDNF by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBDNF is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
    限制
    仅限研究用
  • 状态
    Lyophilized
    储存条件
    -20 °C
    储存方法
    BDNF antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    别名
    BDNF (BDNF 产品)
    别名
    ANON2 antibody, BULN2 antibody, bdnf-A antibody, BDNF antibody, bdnf antibody, brain derived neurotrophic factor antibody, brain-derived neurotrophic factor antibody, brain-derived neurotrophic factor L homeolog antibody, brain-derived neurotrophic factor S homeolog antibody, BDNF antibody, Bdnf antibody, bdnf antibody, bdnf.L antibody, bdnf.S antibody
    背景
    Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. All neurotrophins have six conserved cysteine residues and share a 55 % sequence identity at the amino acid level. BDNF is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. BDNF has been shown to enhance the survival and differentiation of several classes of neurons in vitro, including neural crest and placode derived sensory neurons, dopaminergic neurons in the substantia nigra, basal forebrain cholinergic neurons, hippocampal neurons, and retinal ganglial cells. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields, raising the possibility that BDNF has paracrine or even autocrine actions on neurons as well as non neuronal cells. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. In addition, functional studies showed that age-associated changes in BDNF-mediated pathways can enhance inflammation and increase myocardial injury after myocardial infarction in the aging heart.
    基因ID
    627
    UniProt
    P23560
    途径
    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
You are here:
客服