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AIMP2 抗体 (AA 150-200)

AIMP2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5688957
发货至: 中国
  • 抗原 See all AIMP2 抗体
    AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
    抗原表位
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-200
    适用
    • 25
    • 23
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 37
    • 3
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIMP2 antibody is un-conjugated
    应用范围
    • 33
    • 13
    • 13
    • 8
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    AIMP2 antibody is human specific. AIMP2 antibody is predicted to not cross-react with AIMP1.
    纯化方法
    AIMP2 antibody is affinity chromatography purified via peptide column.
    免疫原
    AIMP2 antibody was raised against a 16 amino acid peptide near the center of human AIMP2.

    The immunogen is located within amino acids 150 - 200 of AIMP2.
    亚型
    IgG
    Top Product
    Discover our top product AIMP2 Primary Antibody
  • 应用备注
    AIMP2 antibody can be used for detection of AIMP2 by Western blot at 1 - 2 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    AIMP2 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    AIMP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
    别名
    AIMP2 (AIMP2 产品)
    别名
    jtv1 antibody, MGC53242 antibody, pro0992 antibody, JTV1 antibody, JTV-1 antibody, P38 antibody, AA407136 antibody, AA407225 antibody, Aimp2(p38) antibody, Jtv1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, aimp2.L antibody, aimp2 antibody, AIMP2 antibody, Aimp2 antibody
    背景
    AIMP2 was initially identified as a part of an aminoacyl-tRNA synthesase complex (1). It was later discovered to be a cofactor and substrate of Parkin, a Ring-type E3 ubiquitin ligase that is important for the survival of dopamine neurons in Parkinson's disease, accumulation of AIMP2 in these cells lead to catecholaminergic cell death (2). AIMP2 can also bind to TRAF2, a key player in the TNF-alpha signaling pathway, causing the ubiquitination of TRAF2 by cIAP1, leading to TNF-alpha-dependent apoptosis (3). Finally, AIMP2 has been suggested to function as a tumor suppressor (4).
    分子量
    Predicted: 35 kDa

    Observed: 36 kDa
    基因ID
    7965
    NCBI登录号
    NP_006294
    UniProt
    Q13155
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