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AIMP2 抗体 (AA 150-200)
AIMP2
适用: 人
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
AIMP2抗体详情
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抗原
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AIMP2
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
抗原表位
All epitopes for AIMP2 抗体
AA 150-200
适用
All reactivities for AIMP2 抗体
人
宿主
All hosts for AIMP2 抗体
兔
克隆类型
All clonalities for AIMP2 抗体
多克隆
标记
All conjugates for AIMP2 抗体
This AIMP2 antibody is un-conjugated
应用范围
All applications for AIMP2 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
特异性
AIMP2 antibody is human specific. AIMP2 antibody is predicted to not cross-react with AIMP1.
纯化方法
AIMP2 antibody is affinity chromatography purified via peptide column.
免疫原
AIMP2 antibody was raised against a 16 amino acid peptide near the center of human AIMP2. The immunogen is located within amino acids 150 - 200 of AIMP2.
亚型
IgG
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Alternatives
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使用细节
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应用备注
AIMP2 antibody can be used for detection of AIMP2 by Western blot at 1 - 2 μ,g/mL.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
AIMP2 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
AIMP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
AIMP2目标详情
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抗原
AIMP2
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
别名
AIMP2 (AIMP2 产品 )
别名
jtv1 antibody, MGC53242 antibody, pro0992 antibody, JTV1 antibody, JTV-1 antibody, P38 antibody, AA407136 antibody, AA407225 antibody, Aimp2(p38) antibody, Jtv1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, aimp2.L antibody, aimp2 antibody, AIMP2 antibody, Aimp2 antibody
背景
AIMP2 was initially identified as a part of an aminoacyl-tRNA synthesase complex (1). It was later discovered to be a cofactor and substrate of Parkin, a Ring-type E3 ubiquitin ligase that is important for the survival of dopamine neurons in Parkinson's disease, accumulation of AIMP2 in these cells lead to catecholaminergic cell death (2). AIMP2 can also bind to TRAF2, a key player in the TNF-alpha signaling pathway, causing the ubiquitination of TRAF2 by cIAP1, leading to TNF-alpha-dependent apoptosis (3). Finally, AIMP2 has been suggested to function as a tumor suppressor (4).
分子量
Predicted: 35 kDa Observed: 36 kDa
基因ID
7965
NCBI登录号
NP_006294
UniProt
Q13155
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