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IFT57 抗体 (AA 159-193)

IFT57 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647795
发货至: 中国
  • 抗原 See all IFT57 抗体
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 159-193
    适用
    • 29
    • 21
    • 17
    • 1
    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFT57 antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应 (详细)
    Expected species reactivity: Bovine
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 159-193 from the human protein was used as the immunogen for the HIPPI antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product IFT57 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting points. Titration of the HIPPI antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:2000
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the HIPPI antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    别名
    HIPPI (IFT57 产品)
    别名
    Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
    背景
    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
    UniProt
    Q9NWB7
    途径
    Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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