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- 抗原 See all ELANE 抗体
- ELANE (Elastase, Neutrophil Expressed (ELANE))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELANE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity purified
- 免疫原
- Amino acids S27-N265 from the mouse protein were used as the immunogen for the Neutrophil Elastase antibody.
- 亚型
- IgG
- Top Product
- Discover our top product ELANE Primary Antibody
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anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibody
ELANE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-247) antibodyELANE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6G6 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 101-200) antibodyELANE 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibodyELANE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC, FACS 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 168-267) antibodyELANE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
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- 应用备注
- Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Neutrophil Elastase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- ELANE (Elastase, Neutrophil Expressed (ELANE))
- 别名
- Neutrophil Elastase (ELANE 产品)
- 别名
- ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
- 背景
- Neutrophil elastase, also called Elane, is a serine protease of neutrophil and monocyte granules. Its key physiologic role is in innate host defense, but it can also participate in tissue remodeling and possesses secretagogue actions important to local inflammatory responses. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
- UniProt
- Q3UP87
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