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CTLA4 抗体

CTLA4 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647509
发货至: 中国
  • 抗原 See all CTLA4 抗体
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    适用
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    小鼠, 大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This CTLA4 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    A recombinant mouse protein corresponding to amino acids E36-D161 was used as the immunogen for the CTLA-4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • 应用备注
    Optimal dilution of the CTLA-4 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free formulation available)
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the CTLA-4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CTLA-4 / CD152 (CTLA4 产品)
    别名
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    背景
    CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.
    UniProt
    P09793
    途径
    Cancer Immune Checkpoints
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