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FGF19 抗体

FGF19 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647123
发货至: 中国
  • 抗原 See all FGF19 抗体
    FGF19 (Fibroblast Growth Factor 19 (FGF19))
    适用
    • 43
    • 4
    • 3
    • 2
    大鼠
    宿主
    • 36
    • 7
    • 1
    克隆类型
    • 39
    • 5
    多克隆
    标记
    • 25
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF19 antibody is un-conjugated
    应用范围
    • 34
    • 23
    • 12
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids R26-K218 from the rat protein were used as the immunogen for the FGF19 antibody.
    亚型
    IgG
    Top Product
    Discover our top product FGF19 Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the FGF19 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    FGF19 (Fibroblast Growth Factor 19 (FGF19))
    别名
    FGF19 (FGF19 产品)
    别名
    FGF-19 antibody, Fgf15 antibody, fibroblast growth factor 19 antibody, FGF19 antibody, Fgf19 antibody, fgf19 antibody
    背景
    FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity. The orthologous protein in mouse is FGF15, which shares about 50 % amino acid identity and has similar functions. Together they are often referred to as FGF15/19.
    UniProt
    Q8VI81
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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