FGF19 抗体
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北京 101111
Quick Overview for FGF19 抗体 (ABIN1169397)
抗原
See all FGF19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-FGF-19 (human), mAb (FG369-1)
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特异性
- Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot.
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产品特性
- Monoclonal Antibody. Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: FG369-1. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human FGF-19.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- FGF19 (Fibroblast Growth Factor 19 (FGF19))
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别名
- FGF-19
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背景
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Alternate Names/Synonyms: Fibroblast Growth Factor 19
Product Description: FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
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UniProt
- O95750
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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