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AIRE 抗体

AIRE 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647007
发货至: 中国
  • 抗原 See all AIRE 抗体
    AIRE (Autoimmune Regulator (AIRE))
    适用
    • 51
    • 23
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    人, 大鼠
    宿主
    • 46
    • 7
    • 1
    克隆类型
    • 53
    多克隆
    标记
    • 38
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIRE antibody is un-conjugated
    应用范围
    • 39
    • 25
    • 19
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids M1-K120 from the human protein were used as the immunogen for the AIRE antibody.
    亚型
    IgG
    Top Product
    Discover our top product AIRE Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution, store at 4°C. After reconstitution, the AIRE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    AIRE (Autoimmune Regulator (AIRE))
    别名
    AIRE (AIRE 产品)
    别名
    AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
    背景
    The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
    UniProt
    O43918
    途径
    Chromatin Binding
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