BAK1 抗体 (AA 29-187)
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- 抗原 See all BAK1 抗体
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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抗原表位
- AA 29-187
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BAK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. coli.
- 克隆位点
- 2H9H7
- 亚型
- IgG2b
- Top Product
- Discover our top product BAK1 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- 别名
- BAK1 (BAK1 产品)
- 别名
- BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
- 背景
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Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Aliases: BAK, CDN1, BCL2L7, BAK-LIKE
- 分子量
- 23.4 kDa
- 基因ID
- 578
- HGNC
- 578
- 途径
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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